Immunodiffusion Analysis of Yaba Poxvirus Structural and Associated Antigens
نویسندگان
چکیده
منابع مشابه
Complete genomic sequence and comparative analysis of the tumorigenic poxvirus Yaba monkey tumor virus.
The Yatapoxvirus genus of poxviruses is comprised of Yaba monkey tumor virus (YMTV), Tanapox virus, and Yaba-like disease virus (YLDV), which all have the ability to infect primates, including humans. Unlike other poxviruses, YMTV induces formation of focalized histiocytomas upon infection. To gain a greater understanding of the Yatapoxvirus genus and the unique tumor formation properties of YM...
متن کاملAlterations of enzymes associated with plasma membranes and cellular organelles during infection of CV-1 cells with Yaba tumor poxvirus.
The formation of cellular aggregates (foci) in CV-1 cells following infection with Yaba tumor poxvirus is dependent upon cell passage level, temperatue of incubation, and calcium concentration in the medium. Resistance of older cells can be reversed by maintaining calcium at 0.1 mM or by adding cortisone acetate (1 mug/ml), hydrocortisone, or estradiol-17beta to the cultures. In susceptible cel...
متن کاملRibonucleotide ReducÃ-aseActivity in Cell-free Extracts of Yaba Poxvirus Tumor and Normal Monkey Tissues1
Ribonucleotide reductase activity in cell-free tissue extracts from Yaba monkey tumors, spleen, kidney, liver, and muscle has been measured in vitro. The specific activity of the enzyme in the Yaba tumor extracts was approximately two times that observed in normal muscle tissue extracts and ten times that in normal liver, spleen and kidney extracts. The specific activity in Yaba tumor extracts ...
متن کاملYaba tumor poxvirus synthesis in vitro. II. Adsorption, inactivation, and assay studies.
Yohn, David S. (Roswell Park Memorial Institute, Buffalo, N.Y.), Fanny R. Marmol, Victoria A. Haendiges, and James T. Grace, Jr. Yaba tumor poxvirus synthesis in vitro. II. Adsorption, inactivation, and assay studies. J. Bacteriol. 91:1953-1958. 1966.-Means to increase the efficiency of the Yaba tumor poxvirus assay in BSC-1 cell cultures were sought. A method was devised wherein 0.4 ml of each...
متن کاملYaba-like disease virus: an alternative replicating poxvirus vector for cancer gene therapy.
Vaccinia virus is being investigated as a replicating vector for tumor-directed gene therapy. However, the majority of cancer patients have preformed immunologic reactivity against vaccinia virus, as a result of smallpox vaccination, which may limit its use as a vector. The Yaba-like disease (YLD) virus was investigated here as an alternative, replicating poxvirus for cancer gene therapy. We ha...
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ژورنال
عنوان ژورنال: Journal of Virology
سال: 1970
ISSN: 0022-538X,1098-5514
DOI: 10.1128/jvi.5.2.212-220.1970